There is widespread traffic disruption in the city following the accident and gardaí are diverting traffic away from the O'Connell Street and Parnell Street areas.
Luas Red Line services are only operating between Tallaght and Smithfield as a result.
Most Dublin Bus services, that would usually use O'Connell St, are diverting via Gardiner St instead.
O'Connell Street northbound is closed and will remain so until at least 7.30pm this evening.
However, the southbound side of the street has re-opened.